Regeneracinės medicinos skyrius

1. kamieninių ląstelių panaudojimas kremzlės reparacijai;
2. MKL kultūros 3D biokarkasuose;
3. chondroprogenitorių paieška žmogaus kremzlėje;
4. reumatoidiniu artritu sergančių pacientų agresyvių sinovijos ląstelių žymenų paieška;
5. vykdomi eksperimentai, norint įvertinti fotodinaminės terapijos poveikį sinovijos ląstelėms, jas panaudojant kaip modelį pacientams, sergantiems reumatoidiniu artritu;
6. kamieninių ląstelių panaudojimas širdies ligų gydymui;
7. MKL panaudojimas plaučių reparacijai gydant plaučių ligas.

Regeneracinės medicinos skyrius 2010 – 2014 metais vykdė FP7 projekto ADIPOA dalį, kur buvo vertinamos riebalinio audinio kamieninių ląstelių panaudojimo osteoartrito gydymui galimybės.

Skyriuje esanti kamieninių ląstelių laboratorija yra puikiai aprūpinta įranga, skirta dirbti su ląstelių kultūromis. Joje yra:

• O₂/CO₂ inkubatorius
• tėkmės citometras/rūšiuoklis FACS Aria
• magnetinis ląstelių separatorius MACS
• fluorescentiniai mikroskopai (tiesioginis ir invertuotas)
• elektroninis mikroskopas
• įranga atlikti PGR, RL-PGR
• elektroporacijos sistema
• ypač žemos temperatūros šaldiklis (-150^oC)
• ELISA skaitytuvo sistema
• įranga, reikalinga histologiniams tyrimams
• kriostatas ir kt.

1. Epigenetinių modifikatorių poveikio reumatoidinio artrito sinovijos fibroblastams (RASF) tyrimai. Temos vadovas: dr.E.Bagdonas. Temos vykdytojai: J. Denkovskij. Temos trukmė: 2015-2017 m.
2. Kamieninių ir aukštesnės diferenciacijos ląstelių funkcinių ypatybių tyrimai. Temos vadovas: dr. E. Bernotienė. Temos vykdytojai: dr. E. Bagdonas, J. Denkovskij, dr. A. Ungurytė, prof. Z. Mackevič. Temos trukmė: 2015-2017 m.
3. Regeneracinių organizmo galimybių ir mechanizmų tyrimai ir jais pagrįstų gydymo technologijų kūrimas. Temos vadovas: dr. D. Bironaitė. Temos vykdytojai: dr .D. Bironaitė. Temos trukmė: 2015 m.
4. Plaučių alveolinio audinio regeneracijos mechanizmų tyrimai. Temos vadovas: dr. R. Aldonytė. Temos vykdytojai: J. Raudoniūtė, dr. A. Ungurytė, dr. S. Abaravičienė. Temos trukmė: 2014-2017 m.

• Vailionytė Agnė

2021-10-01 – 2025-09-30

Vadovė – dr. Rūta Aldonytė

Tema - Žmogaus kvėpavimo sistemos organų audinių ir ligų biomodeliai in vitro.

• Pachaleva Jolita

2021-10-01 – 2025-09-30

Vadovė – dr. Eiva Bernotienė

Tema - Kamieninėmis ląstelėmis paremtų technologijų taikymas skeleto audinių degeneracijos slopinimui bei regeneracijos žymenų paieška.

• Kugaudaitė Gabija

2024-10-01 – 2028-09-30

Vadovas – dr. Ilona Uzielienė

Tema - Žmogaus kamieninių ląstelių panaudojimas kremzlės audinio regeneracijai.

2025 metai

Publikacijos leidiniuose, referuojamuose ir turinčiuose citavimo indeksą mokslinės informacijos instituto duomenų bazėje "Clarivate Analytivs Web of Science :

1. King, L.K., Liew, J.W., Mahmoudian, A., Wang, Q., Jansen, N.E.J., Stanaitis, I., Hung, V., Berenbaum, F., Das, S., Ding, C., Emery, C.A., Filbay, S.R., Hochberg, M.C., Ishijima, M., Kloppenburg, M., Lane, N.E., Losina, E., Mobasheri, A., Turkiewicz, A., Runhaar, J., Haugen, I.K., Appleton, C.T., Lohmander, L.S., Englund, M., Neogi, T., Hawker, G.A.; OARSI Early-stage Symptomatic Knee Osteoarthritis Initiative. (2025). Multi-centre modified delphi exercise to identify candidate items for classifying early-stage symptomatic knee osteoarthritis. Osteoarthritis and Cartilage, 33(1), 155-165.
2. Hannani, M.T., Thudium, C.S., Gellhorn, A.C., Larkin, J., Karsdal, M.A., Lisowska-Petersen, Z., Frederiksen, P., Bager, C.L., Ladel, C., Struglics, A., Uebelhoer, M., Henrotin, Y., Bihlet, A.R., Blanco, F.J., Haugen, I.K., Kloppenburg, M., Berenbaum, F., Mobasheri, A., Bacardit, J., Bay-Jensen, A.C. (2025). Longitudinal stability of molecular endotypes of knee osteoarthritis patients. Osteoarthritis and Cartilage, 33(1), 166-175.
3. Piven, O.O., Vaičiulevičiūtė, R., Bernotienė, E., Dobrzyn, P. (2025). Cardiomyocyte engineering: the meeting point of transcription factors, signaling networks, metabolism and function. Acta Physiologica, 241(2), e14271.
4. Pajarskienė, J., Vailionytė, A., Uogintė, I., Byčenkienė, S., Jonavičė, U., Uzielienė, I., Bagdonas, E., Aldonytė, R. (2025). Efects of carbon black particles on human monocyte‑derived macrophages: type‑dependent pro‑infammatory activation in vitro. Archives of Toxicology,  99(2), 787-796.
5. Zheng, L., Gu, M., Li, X., Hu, X., Chen, C., Kang, Y., Pan, B., Chen, W., Xian, G., Wu, X., Li, C., Wang, C., Li, Z., Guan, M., Zhou, G., Mobasheri, A., Song, W., Peng, S., Sheng, P., Zhang, Z. (2025). ITGA5+ synovial fibroblasts orchestrate proinflammatory niche formation by remodelling the local immune microenvironment in rheumatoid arthritis. Annals of the Rheumatic Diseases, 84(2), 232-252.
6. Kalvaitytė, U., Bagdonas E., Kirdaitė, G., Kaušaitė-Minkštimienė, A., Uzielienė I., Ramanavičienė, A., Popov, A., Butkienė, G., Karabanovas, V., Denkovskij, J., Mobasheri, A., Bernotienė, E. (2025). Development of a sensitive quantum dot-linked immunoassay for the multiplex detection of biochemical markers in a microvolumeric format. International Journal of Nanomedicine, 20, 1717-1729.
7. Tran, H., Tauro, W., Mobasheri, A., Noh, M.J. (2024). TissueGene-C induces anti-inflammatory activity and M2 macrophage polarization via activation of prostaglandin E2 signaling. Cytotherapy, 27(3), 324-337.

2024 metai

Publikacijos leidiniuose, referuojamuose ir turinčiuose citavimo indeksą mokslinės informacijos instituto duomenų bazėje "Clarivate Analytivs Web of Science :

1. Uzielienė, I., Popov, A., Vaičiulevičiūtė, R., Kirdaitė, G., Bernotienė, E., Ramanavičienė A. (2024). Polypyrrole-based structures for activation of cellular functions under electrical stimulation. Bioelectrochemistry, 155, 108585.
2. Hannani, M.T., Thudium, C.S., Karsdal, M.A., Ladel, C., Mobasheri, A., Uebelhoer, M., Larkin, J., Bacardit, J., Struglics, A., Bay-Jensen, A.C. (2024). From biochemical markers to molecular endotypes of osteoarthritis: a review on validated biomarkers. Expert Review of Molecular Diagnostics, 24(1), 23-38.
3. Mobasheri. A., Spring-Charles, A., Gamaleri, F.C., McSwan, J., Garg, M., Sethi, V.S. (2024). Evidence-based opinions from multidisciplinary experts on use of naturopathic herbal remedies in pain management. Journal of Pain Research, 17, 599-608.
4. Ardatov, O., Pachaleva, J., Aleksiuk, V., Maknickas, A., Uzielienė, I., Vaičiulevičiūtė, R., Bernotienė, E. (2024). Modeling the Effect of Annulus Fibrosus Stiffness on the Stressed State of a Vertebral L1 Body and Nucleus Pulposus. Bioengineering, 11(4), 305.
5. Mazėtytė-Godienė, A., Vailionytė, A., Jelinskas, T., Denkovskij, J., Ūsas, A. (2024). Promotion of hMDSC differentiation by combined action of scaffold material and TGF-β superfamily growth factors. Regenerative Therapy, 27, 307-318.
6. Konovalovas, A., Armalytė, J., Klimkaitė, L., Liveikis, T., Jonaitytė, B., Danila, E., Bironaitė, D., Mieliauskaitė, D., Bagdonas, E., Aldonytė, R. (2024). Human nasal microbiota shifts in healthy and chronic respiratory disease conditions. BMC Microbiology, 24(1), 150.
7. Bagdonienė, L., Bagdonas, E., Ridikaitė, E., Baniukaitienė, O., Pečiulytė, L., Pupiūtė, A., Martuzevičius, D., Krugly, E. (2024). Enhancing 3D poly[ε]caprolactone scaffold properties through alkaline hydrolysis for improved chondrocyte culture: morphological, physicochemical, and biocompatibility evaluations. Journal of Drug Delivery Science and Technology, 97, 105806.
8. Li, H.Z., Zhang, J.L., Yuan, D.L., Xie, W.Q., Ladel, C.H., Mobasheri, A., Li, Y.S. (2024) Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family. Military Medical Research, 11(1), 40.
9. Mikšiūnas, R., Labeit, S., Bironaitė, D. (2024). Class I and II histone deacetylase inhibitors as therapeutic modulators of dilated cardiac tissue-derived mesenchymal stem/stromal cells. International Journal of Molecular Sciences, 25(12), 6758.
10. Primorac, D., Molnar, V., Tsoukas, D., Uzielienė, I., Tremolada, C., Brlek, P., Klaric, E., Vidovic, D., Zekusic, M., Pachaleva, J., Bernotienė, E., Wilson, A., Mobasheri, A. (2024). Tissue engineering and future directions in regenerative medicine for knee cartilage repair: a comprehensive review. Croatian Medical Journal, 65(3), 268-287.
11. Bujanauskienė, D., Merkevičius, K., Kuliešiūtė, U., Denkovskij, J., Kutanovas, S., Lukšys, G., Ročka, S., Bernotienė, E., Neniškytė, U. (2024). Integrity assay for messenger RNA in mouse and human brain samples and synaptosomal preparations. iScience, 27(8), 110419.
12. Mobasheri, A., Loeser, R. (2024). Clinical phenotypes, molecular endotypes and theratypes in OA therapeutic development. Nature Reviews Rheumatology, 20(9), 525-526.
13. Krugly, E., Bagdonas, E., Raudoniūtė, J., Ravikumar, P., Bagdonienė, L., Čiužas, D., Prasauskas, T., Aldonytė, R., Gutleb, A.C., Martuzevičius, D. (2024). A novel "cells-on-particles" cytotoxicity testing platform in vitro: design, characterization, and validation against engineered nanoparticle aerosol. Toxicology, 508, 153936.
14. Kaunelienė, V., Bagdonas, E., Aldonytė, R., Raudoniūtė, J., Čiužas, D., Bagdonienė, L., Pocevičiūtė, G., Prasauskas, T., Krugly, E., Martuzevičius, D. (2024). Cytotoxicity of the exhaled aerosol particles from the usage of conventional cigarette and heated tobacco product as determined by a novel “Cells-on-Particles” exposure model in vitro. Environmental Pollution, 361, 124870.
15. Kast, S., Kemmler, W., Roemer, F.W., Kohl, M., Culvenor, A.G., Mobasheri, A., Uder, M., von Stengel, S. (2024). Effectiveness of whole-body electromyostimulation on knee pain and physical function in knee osteoarthritis: a randomized controlled trial. Scientifc Reports, 14(1), 20804.
16. Kistamás, K., Lamberto, F., Vaičiulevičiūtė, R., Leal, F., Muenthaisong, S., Marte, L., Subias-Beltrán, P., Alaburda, A., Arvanitis, D.N., Zana, M., Costa, P.F., Bernotienė, E., Bergaud, C., Dinnyés, A. (2024). The current state of realistic heart models for disease modelling and cardiotoxicity. International Journal of Molecular Sciences, 25(17), 9186.
17. Butkienė, G., Daugelaitė, A.M., Poderys, V., Marin, R., Steponkienė, S., Kazlauskė, E., Uzielienė, I., Daunoravičius, D., Jaque, D., Rotomskis, R., Skripka, A., Vetrone, F., Karabanovas, V. (2024). Synergistic enhancement of photodynamic cancer therapy with mesenchymal stem cells and theranostic nanoparticles. ACS Applied Materials & Interfaces, 16(37), 49092-49103.
18. Kasputė, G., Bareikienė, E., Prentice, U., Uzielienė, I., Ramašauskaitė, D., Ivaškienė, T. (2024). A comprehensive review of advanced diagnostic techniques for endometriosis: new approaches to improving women’s well-being. Medicina-Lithuania, 60(11), 1866.
19. Mobasheri, A., Rannou, F., Ivanavicius, S., Conaghan, P,G. (2024). Targeting the TRPV1 pain pathway in osteoarthritis of the knee. Expert Opinion on Therapeutic Targets, 28(10), 843-856.
20. Aziz, A., Nathan, K.G., Kamarul, T., Mobasheri, A., Sharifi, A. (2024). The interplay between dysregulated metabolites and signaling pathway alterations involved in osteoarthritis: a systematic review. Therapeutic Advances in Musculoskeletal Disease, 16, 1759720X241299535.
21. Kirdaitė, G., Denkovskij, J., Mieliauskaitė, D., Pachaleva, J., Bernotienė, E. (2024). The challenges of local intra-articular therapy. Medicina-Lithuania, 60(11), 1819.
22. Konovalovas, A., Armalytė, J., Klimkaitė, L., Liveikis, T., Jonaitytė, B., Danila, E., Bironaitė, D., Mieliauskaitė, D., Bagdonas, E., Aldonytė, R. (2024). Insights into respiratory microbiome composition and systemic inflammatory biomarkers of bronchiectasis patients. Microbiology Spectrum,  12(12), e04144-23.
23. Mobasheri, A., Matta, C., Giles, W., Rajnicek, A.M., Ivanavicius, S. (2024). Ion channels as emerging metabolic regulators and therapeutic targets in osteoarthritis: Nav1.7 as a recent exemplar. Bioelectricity, 6(1), 54-56.
24. Mobasheri, A., Matta, C., Giles, W., Choi, H., Ivanavicius, S. (2024). The interplay between inflammatory mediators and mechanotransduction is mediated by ion channels in articular chondrocytes: Functional consequences in osteoarthritis. Physics of Life Reviews, 49, 123-126.
25. Dvir-Ginzberg, M., Maatuf, Y.H., Mobasheri, A. (2024). Do we understand sex-related differences governing dimorphic disease mechanisms in preclinical animal models of osteoarthritis? Osteoarthritis and Cartilage, 32(9), 1054-1057.

Publikacijos kituose recenzuojamuose mokslo leidiniuose:

1. Duong, V., Bunzli, S., Callahan, L.F., Baatenburg de Jong, C., Hunter, D.J., Kim, J.S., Mobasheri, A. (2024). Visual narratives in medicine - bridging the gap in graphic medicine with an illustrated narrative of osteoarthritis. Osteoarthritis and Cartilage Open, 6(2), 100471.
2. Henriques, J., Berenbaum, F., Mobasheri, A. (2024). Obesity-induced fibrosis in osteoarthritis: pathogenesis, consequences and novel therapeutic opportunities. Osteoarthritis and Cartilage Open, 6(4), 100511.
3. Peitso, V., Sarmadian, Z., Henriques, J., Lauwers, E., Paggi, C.A., Mobasheri, A. (2024). Development of a microphysiological cartilage-on-chip platform for dynamic biomechanical stimulation of three-dimensional encapsulated chondrocytes in agarose hydrogels. Current Protocols, 4(12), e70079.

2023 metai

Publikacijos leidiniuose, referuojamuose ir turinčiuose citavimo indeksą mokslinės informacijos instituto duomenų bazėje "Clarivate Analytivs Web of Science:

1. Fosse, V., Oldoni, E., Bietrix, F., Budillon, A., Daskalopoulos, E.P., Fratelli, M., Gerlach, B., Groenen, P.M.A., Hölter, S.M., Menon, J.M.L., Mobasheri, A., Osborne, N., Ritskes-Hoitinga, M., Ryll, B., Schmitt, E., Ussi, A., Andreu, A.L., McCormack, E. (2023). Recommendations for robust and reproducible preclinical research in personalised medicine. BMC Medicine, 21(1), 14.
2. Ladang, A., Beaudart, C., Reginster, J.Y., Al-Daghri, N., Bruyère, O., Burlet, N., Cesari, M., Cherubini, A., da Silva, M.C., Cooper, C., Cruz-Jentoft, A.J., Landi, F., Laslop, A., Maggi, S., Mobasheri, A., Ormarsdottir, S., Radermecker, R., Visser, M., Yerro, M.C.P., Rizzoli, R., Cavalier, E. (2023). Biochemical markers of musculoskeletal health and aging to be assessed in clinical trials of drugs aiming at the treatment of sarcopenia: consensus paper from an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the Centre Académique de Recherche et d'Expérimentation en Santé (CARES SPRL), under the auspices of the World Health Organization Collaborating Center for the Epidemiology of Musculoskeletal Conditions and Aging. Calcified Tissue International, 112(2), 197-217.
3. Raudoniūtė, J., Bironaitė, D., Bagdonas, E., Kulvinskienė, I., Jonaitytė, B., Danila, E., Aldonytė, R. (2023). Human airway and lung microbiome at the crossroad of health and disease (Review). Experimental and Therapeutic Medicine, 25(1), 18.
4. Uzielienė, I., Bironaitė, D., Bagdonas, E., Pachaleva, J., Sobolev, A., Tsai, W.B., Kvederas, G., Bernotienė E. (2023). The effects of mechanical load on chondrogenic responses of bone marrow mesenchymal stem cells and chondrocytes encapsulated in chondroitin sulfate-based hydrogel. International Journal of Molecular Sciences, 24(3), 2915.
5. Uzielienė, I., Bironaitė, D., Pachaleva, J., Bagdonas, E., Sobolev, A., Tsai, W.B., Kvedaras, G., Bernotienė, E. (2023). Chondroitin sulfate-tyramine-based hydrogels for cartilage tissue repair. International Journal of Molecular Sciences, 24(4), 3451.
6. Ardatov, O., Aleksiuk, V., Maknickas, A., Stonkus, R., Uzielienė, I., Vaičiulevičiūtė, R., Pachaleva, J., Kvederas, G., Bernotienė, E. (2023). Modeling the impact of meniscal tears on von mises stress of knee cartilage tissue. Bioengineering, 10, 314.
7. van Helvoort, E.M., Jansen, M.P., Marijnissen, A.C.A., Kloppenburg, M., Blanco, F.J., Haugen, I.K., Berenbaum, F., Bay-Jensen, A.C.C., Ladel, C., Lalande, A., Larkin, J., Loughlin, J., Mobasheri, A., Weinans, H.H., Widera, P., Bacardit, J., Welsing, P.M.J., Lafeber, F.P.J.G. (2023). Predicted and actual 2-year structural and pain progression in the IMI-APPROACH knee osteoarthritis cohort. Rheumatology(Oxford), 62(1), 147–157.
8. Gudauskaitė, G., Kairienė, I., Ivaškienė, T., Rascon, J., Mobasheri, A. (2023). Therapeutic perspectives for the clinical application of umbilical cord hematopoietic and mesenchymal stem cells: overcoming complications arising after allogeneic hematopoietic stem cell transplantation. Advances in Experimental Medicine and Biology, 1409, 111-126.
9. Vaičiulevičiūtė, R., Uzielienė, I., Bernotas, P., Novickij, V., Alaburda, A., Bernotienė, E. (2023). Electrical stimulation in cartilage tissue engineering. Bioengineering, 10(4), 454.
10. Guermazi. A., Roemer, F.W., Crema, M.D., Jarraya, M., Mobasheri, A., Hayashi, D. (2023). Strategic application of imaging in DMOAD clinical trials: focus on eligibility, drug delivery, and semiquantitative assessment of structural progression. Therapeutic Advances in Musculoskeletal Disease, 15, 1759720X231165558.
11. Ruiz-Fernández, C., Ait Eldjoudi, D., González-Rodríguez, M., Cordero Barreal, A., Farrag, Y., García-Caballero, L., Lago, F., Mobasheri, A., Sakai, D., Pino, J., Gualillo, O. (2023). Monomeric CRP regulates inflammatory responses in human intervertebral disc cells. Bone & Joint Research, 12(3), 189-198.
12. Uzielienė, I., Bironaitė, D., Mikšiūnas, R., Bagdonas, E., Vaičiulevičiūtė, R., Mobasheri, A., Bernotienė, E. (2023). The effect of CaV1.2 inhibitor nifedipine on chondrogenic differentiation of human bone marrow or menstrual blood-derived mesenchymal stem cells and chondrocytes. International Journal of Molecular Sciences,  24(7), 6730.
13. Driban, J.B., Vincent, H.K., Trojian, T.H., Ambrose, K.R., Baez, S., Beresic, N., Berkoff, D.J., Callahan, L.F., Cohen, B., Franek, M., Golightly, Y.M., Harkey, M., Kuenze, C.M., Minnig, M.C., Mobasheri, A., Naylor, A., Newman, C.B., Padua, D.A., Pietrosimone, B., Pinto, D., Root, H., Salzler, M., Schmitt, L., Snyder-Mackler, L., Taylor, J.B., Thoma, L.M., Vincent, K.R., Wellsandt, E., Williams, M. (2023). Evidence review for preventing osteoarthritis after an anterior cruciate ligament injury: an osteoarthritis action alliance consensus statement. Journal of Athletic Training, 58(3), 198-219.
14. Kovács, P., Pushparaj, P.N., Takács, R., Mobasheri, A., Matta, C. (2023). The clusterin connectome: Emerging players in chondrocyte biology and putative exploratory biomarkers of osteoarthritis. Frontiers in Immunology, 14, 1103097.
15. Driban, J.B., Vincent, H.K., Trojian, T.H., Ambrose, K.R., Baez, S., Beresic, N., Berkoff, D.J., Callahan, L.F., Cohen, B., Franek, M., Golightly, Y.M., Harkey, M., Kuenze, C.M., Minnig, M.C., Mobasheri, A., Naylor, A., Newman, C.B., Padua, D.A., Pietrosimone, B., Pinto, D., Root, H., Salzler, M., Schmitt, L.C., Snyder-Mackler, L., Taylor, J.B., Thoma, L.M., Vincent, K.R., Wellsandt, E., Williams, M. (2023). Preventing osteoarthritis after an anterior cruciate ligament injury: an osteoarthritis action alliance consensus statement. Journal of Athletic Training, 58(3), 193-197.
16. Kaušaitė-Minkštimienė, A., Popov, A., Kalvaitytė, U., Bernotienė, E., Mobasheri, A., Ramanavičienė, A. (2023). An ultra-sensitive SPR immunosensor for quantitative determination of human cartilage oligomeric matrix protein biomarker. Biosensors and Bioelectronics, 234, 115370.
17. Uzielienė, I., Popov, A., Lisytė, V., Kugaudaitė, G., Bialaglovytė, P., Vaičiulevičiūtė, R., Kvederas, G., Bernotienė, E., Ramanavičienė, A. (2023). Stimulation of chondrocyte and bone marrow mesenchymal stem cell chondrogenic response by polypyrrole and polypyrrole/gold nanoparticles. Polymers, 15(11), 2571.
18. Alasvand, N., Behnamghader, A., Milan, P.B., Simorgh, S., Mobasheri, A., Mozafari, M. (2023). Tissue-engineered small-diameter vascular grafts containing novel copper-doped bioactive glass biomaterials to promote angiogenic activity and endothelial regeneration. Materials Today Bio, 20, 100647.
19. Matta, C., Takács, R., Ducza, L., Ebeid, A.R., Choi, H., Mobasheri, A. (2023). Ion channels involved in inflammation and pain in osteoarthritis and related musculoskeletal disorders. American Journal of Physiology-Cell Physiology, 325(1), C257-C271.
20. Klimkaitė, L., Liveikis, T., Kasputė, G., Armalytė, J., Aldonytė, R. (2023). Air pollution-associated shifts in the human airway microbiome and exposure-associated molecular events. Future Microbiology, 18(9), 607-623.
21. Kistamas, K., Muller, A., Muenthaisong, S., Lamberto, F., Zana, M., Dulac, M., Leal, F., Maziz, A., Costa, P., Bernotienė, E., Bergaud, C., Dinnyes, A. (2023). Multifactorial approaches to enhance maturation of human iPSC-derived cardiomyocytes. Journal of Molecular Liquids, 387, 122668.
22. Uogintė, I., Vailionytė, A., Skapas, M., Bolanos, D., Bagurskienė, E., Gruslys, V., Aldonytė, R., Byčenkienė, S. (2023). New evidence of the presence of micro- and nanoplastic particles in bronchioalveolar lavage samples of clinical trial subjects. Heliyon, 9(9), e19665. 
23. Karsdal, M.A., Tambiah, J., Felson, D., Ladel, C., Nikolov, N.P., Hodgins, D., Bihlet, A.R., Neogi, T., Baatenburg de Jong, C., Bay-Jensen, A.C., Baron, R., Laslop, A., Mobasheri, A., Kraus, V.B. (2023). Reflections from the OARSI 2022 clinical trials symposium: The pain of OA-Deconstruction of pain and patient-reported outcome measures for the benefit of patients and clinical trial design. Osteoarthritis and Cartilage, 31(10), 1293-1302.
24. Uzielienė, I., Bialaglovytė, P., Mikšiūnas, R., Lebedis, I., Pachaleva, J., Vaičiulevičiūtė, R., Ramanavičienė, A., Kvederas, G., Bernotienė, E. (2023). Menstrual blood-derived stem cell paracrine factors possess stimulatory effects on chondrogenesis in vitro and diminish the degradation of articular cartilage during osteoarthritis. Bioengineering, 10(9), 1001.
25. Aleksiuk, V., Baleišis, J., Kirdaitė, G., Uzielienė, I., Denkovskij, J., Bernotas, P., Ivaškienė, T., Mobasheri, A., Bernotienė, E. (2023). Evaluation of cartilage integrity following administration of oral and intraarticular nifedipine in a murine model of osteoarthritis. Biomedicines, 11(9), 2443.
26. Bironaitė, D., Petronienė, J., Mikšiūnas, R., Zinovičius, A., Morkvėnaitė-Vilkončienė, I., Ramanavičius, A. (2023). Scanning electrochemical microscopy for the stimulation and investigation of human skeletal muscle-derived mesenchymal stem/stromal cells. Electrochimica Acta, 455, 142389.
27. Ommati, M.M., Mobasheri, A., Niknahad, H., Rezaei, M., Alidaee, S., Arjmand, A., Mazloomi, S., Abdoli, N., Sadeghian, I., Sabouri, S., Saeed, M., Mousavi, K., Najibi, A., Heidari, R. (2023). Low-dose ketamine improves animals' locomotor activity and decreases brain oxidative stress and inflammation in ammonia-induced neurotoxicity. Journal of Biochemical and Molecular Toxicology, 37(11), e23468.
28. Park, E.H., Seo, J., Lee, Y., Park, K., Kim, K.R., Kim, S., Mobasheri, A., Choi, H. (2023). TissueGene-C induces long-term analgesic effects through regulation of pain mediators and neuronal sensitization in a rat monoiodoacetate- induced model of osteoarthritis pain. Osteoarthritis and Cartilage, 31(12), 1567-1580.
29. Niknahad, H., Mobasheri, A., Arjmand, A., Rafiei, E., Alidaee, S., Razavi, H., Bagheri, S., Rezaei, H., Sabouri, S., Najibi, A., Khodaei, F., Kashani, S.M.A., Ommati, M.M., Heidari, R. (2023). Hepatic encephalopathy complications are diminished by piracetam via the interaction between mitochondrial function, oxidative stress, inflammatory response, and locomotor activity. Heliyon, 9(10), e20557.
30. Liu, G., Wei, J., Xiao, W., Xie, W., Ru, Q., Chen, L., Wu, Y., Mobasheri, A., Li, Y. (2023). Insights into the Notch signaling pathway in degenerative musculoskeletal disorders: mechanisms and perspectives. Biomedicine & Pharmacotherapy, 169, 115884.
31. Hossain, M.I., Shams, A.B., Das Gupta, S., Blanchard, G.J., Mobasheri, A., Hoque Apu, E. (2023). The potential role of ionic liquid as a multifunctional dental biomaterial. Biomedicines, 11(11), 3093.
32. Rahman, S.O., Bariguian, F., Mobasheri, A. (2023). The potential role of probiotics in the management of osteoarthritis pain: current status and future prospects. Current Rheumatology Reports, 25(12), 307-326.
33. Mobasheri, A., Thudium, C.S., Bay-Jensen, A.-C., Maleitzke, T., Geissler, S., Duda, G.N., Winkler, T. (2023).  Biomarkers for osteoarthritis: current status and future prospects. Best Practice & Research Clinical Rheumatology, 37(2), 101852.

Publikacijos kituose recenzuojamuose mokslo leidiniuose:

1. Otahal, A., De Luna, A., Mobasheri, A., Nehrer, S. (2023). Extracellular vesicle isolation and characterization for applications in cartilage tissue engineering and osteoarthritis therapy. Methods in Molecular Biology, 2598, 123-140.
2. Widera, P., Welsing, P.M.J., Danso, S.O., Peelen, S., Kloppenburg, M., Loef, M., Marijnissen, A.C., van Helvoort, E.M., Blanco, F.J., Magalhaes, J., Berenbaum, F., Haugen, I.K., Bay-Jensen, A.C., Mobasheri, A., Ladel, C., Loughlin, J., Lafeber, F.P.J.G., Lalande, A., Larkin, J., Weinans, H., Bacardit, J. (2023). Development and validation of a machine learning-supported strategy of patient selection for osteoarthritis clinical trials: the IMI-APPROACH study. Osteoarthritis and Cartilage Open, 5(4), 100406.

Monografijos ir jų dalys:

1. Vaičiulevičiūtė, R., Pachaleva, J., Kalvaitytė, U., Aleksiuk, V., Uzielienė, I., Mobasheri, A., Bernotienė, E. (2023). Extracellular matrix biomimicry for cartilage tissue formation.  The Springer Nature book “Cartilage: from Biology to Biofabrication”. In: Cartilage: From Biology to Biofabrication, (eds.), Baghaban Eslaminejad, M., Hosseini, S., 209–253.

2022 metai

Publikacijos leidiniuose, referuojamuose ir turinčiuose citavimo indeksą mokslinės informacijos instituto duomenų bazėje "Clarivate Analytivs Web of Science:

1. Kalvaitytė, U., Matta, C., Bernotienė, E., Pushparaj, P.N., Kiapour, A.M., Mobasheri, A. (2022). Exploring the translational potential of clusterin as a biomarker of early osteoarthritis. Journal of Orthopaedic Translation, 32, 77-84.
2. Ramanavičienė, A., Popov, A., Baliūnaitė, E., Brasiūnas, B., Tamer, U., Kaušaitė-Minkštimienė, A., Kirdaitė, G., Bernotienė, E., Mobasheri, A. (2022). Magneto-immunoassay for the detection and quantification of human growth hormone.  Biosensors, 12(2), 65.
3. Šakalytė, R., Denkovskij, J., Bernotienė, E., Stropuvienė, S., Mikulėnaitė, S.O., Kvederas, G., Porvaneckas, N., Tutkus, V., Venalis, A., Butrimienė, I. (2022). The expression of inflammasomes NLRP1 and NLRP3, Toll-like receptors, and vitamin D receptor in synovial fibroblasts from patients with different types of knee arthritis. Frontiers in Immunology, 12, 767512.
4. Francisco, V., Pino, J., González-Gay, M.A., Lago, F., Karppinen, J., Tervonen, O., Mobasheri, A., Gualillo, O. (2022). A new immunometabolic perspective of intervertebral disc degeneration.  Nature Reviews Rheumatology,  18(1), 47-60.
5. Bay-Jensen, A.C., Mobasheri, A., Thudium, C.S., Virginia B Kraus, V.B., Karsdal, M.A. (2022). Blood and urine biomarkers in osteoarthritis - an update on cartilage associated type II collagen and aggrecan markers. Current Opinion in Rheumatology, 34(1), 54-60.
6. Angelini, F., Widera, P., Mobasheri, A., Blair, J., Struglics, A., Uebelhoer, M., Henrotin, Y., Marijnissen, A.C., Kloppenburg, M., Blanco, F.J., Haugen, I.K., Berenbaum, F., Ladel, C., Larkin, J., Bay-Jensen, A.C., Bacardit, J. (2022). Osteoarthritis endotype discovery via clustering of biochemical marker data. Annals of the Rheumatic Diseases, 81(5), 666-675.
7. Szwedowski, D., Mobasheri, A., Moniuszko, A., Zabrzynski, J., Jeka, S. (2022). Intra-articular injection of platelet-rich plasma is more effective than hyaluronic acid or steroid injection in the treatment of mild to moderate knee osteoarthritis: a prospective, randomized, triple-parallel clinical trial. Biomedicines, 10(5), 991.
8. Strowitzki, M.J., Nelson, R., Garcia, M.P., Tuffs, C., Bleul, M.B., Fitzsimons, S., Navas, J., Uzielienė, I., Ritter, A.S., Phelan, D., Kierans, S.J., Blanco, A., Bernotienė, E., Belton, O., Schneider, M., Cummins, E.P., Taylor, C.T. (2022). Carbon dioxide sensing by immune cells occurs through carbonic anhydrase 2-dependent changes in intracellular pH. Journal of Immunology, 208(10), 2363-2375.
9. Dallo, I., D'Ambrosi, R., Szwedowski, D., Mobasheri, A., Gobbi, A. (2022). Minimally invasive cell-based therapy for symptomatic bone marrow lesions of the knee: a prospective clinical study at 1 year. Stem Cells and Development, 31(15-16), 488-497.
10. Ruiz-Fernandez, C., Gonzalez-Rodriguez, M., Abella, V., Francisco, V., Cordero-Barreal, A., Eldjoudi, D.A., Farrag, Y., Pino, J., Conde-Aranda, J., Gonzalez-Gay, M.A., Mera, A., Mobasheri, A., Garcia-Caballero, L., Gandara-Cortes, M., Lago, F., Scotece, M., Gualillo, O. (2022). WISP-2 modulates the induction of inflammatory mediators and cartilage catabolism in chondromytes. Laboratory Investigation, 102(9), 989-999.
11. Varela-Eirin, M., Carpintero-Fernandez, P., Guitian-Caamano, A., Varela-Vazquez, A., Garcia-Yuste, A., Sanchez-Temprano, A., Bravo-Lopez, S.B., Yanez-Cabanas, J., Fonseca, E., Largo, R., Mobasheri, A., Caeiro, J.R., Mayan, M.D. (2022). Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression. Cell Death & Disease, 13(8), Article Number 681.
12. Oo, W.M., Mobasheri, A., Hunter, D.J. (2022). A narrative review of anti-obesity medications for obese patients with osteoarthritis. Expert Opinion on Pharmacotherapy, 23(12), 1381-1395.
13. Fuggle, N., Bere, N., Bruyere, O., Rosa, M.M., Yerro, M.C.P., Dennison, E., Dincer, F., Gabay, C., Haugen, I.K., Herrero-Beaumont, G., Hiligsmann, M., Hochberg, M.C., Laslop, A., Matijevic, R., Maheu, E., Migliore, A., Pelletier, J.P., Radermecker, R.P., Rannou, F., Uebelhart, B., Uebelhart, D., Veronese, N., Vlaskovska, M., Rizzoli, R., Mobasheri, A., Cooper, C., Reginster, J.Y. (2022). Management of hand osteoarthritis: from an US evidence-based medicine guideline to a European patient-centric approach. Aging Clinical and Experimental Research, 34(9), 1985-1995.
14. Loef, M., van de Stadt, L., Böhringer, S., Bay-Jensen, A-C., Mobasheri, A., Larkin, J., Lafeber, F.P.J.G., Blanco, F.J., Haugen, I.K., Berenbaum, F., Giera, M., Ioan-Facsinay, A., Kloppenburg, M. (2022). The association of the lipid profile with knee and hand osteoarthritis severity: the IMI-APPROACH cohort. Osteoarthritis and  Cartilage, 30(8), 1062-1069.
15. Veronese, N., Cooper, C., Bruyère, O., Al-Daghri, N.M., Branco, J., Cavalier, E., Cheleschi, S., da Silva Rosa, M.C., Conaghan, P.G., Dennison, E.M., de Wit, M., Fioravanti, A., Fuggle, N.R., Haugen, I.K., Herrero-Beaumont, G., Honvo, G., Laslop, A., Matijevic, R., Migliore, A., Mobasheri, A., Pelletier, J.P., Prieto Yerro, M.C., Radermecker, R.P., Rannou, F., Rizzoli, R., Reginster, J.Y. (2022). Multimodal multidisciplinary management of patients with moderate to severe pain in knee osteoarthritis: a need to meet patient expectations. Drugs, 82(13), 1347-1355.
16. Popov, A., Lisytė, V., Kaušaitė-Minkštimienė, A., Bernotienė, E., Ramanavičienė, A. (2022). Experimental evaluation of quantum dots and antibodies conjugation by surface plasmon resonance spectroscopy. International Journal of Molecular Sciences, 23(20), 12626.
17. Väärälä, A., Casula, V., Peuna, A., Panfilov, E., Mobasheri, A., Haapea, M., Lammentausta, E., Nieminen, M.T. (2022). Predicting osteoarthritis onset and progression with 3D texture analysis of cartilage MRI DESS: 6-Year data from osteoarthritis initiative. The Journal of Orthopaedic Research, 40(11), 2597-2608.
18. Ommati, M.M., Mobasheri, A., Ma, Y., Xu, D., Tang, Z., Manthari, R.K., Abdoli, N., Azarpira, N., Lu, Y., Sadeghian, I., Mousavifaraz, A., Nadgaran, A., Nikoozadeh, A., Mazloomi, S., Mehrabani, P.S., Rezaei, M., Xin, H., Mingyu, Y., Niknahad, H., Heidari, R. (2022). Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation. Naunyn-Schmiedebergs Archives of Pharmacology, 395(12), 1557-1572.
19. Mikšiūnas, R., Labeit, S., Bironaitė, D. (2022). The effect of heat shock on myogenic differentiation of human skeletal-muscle-derived mesenchymal stem/stromal cells. Cells, 11(20), 3209.
20. Simorgh, S., Alasvand, N., Khodadadi, M., Ghobadi, F., Malekzadeh Kebria, M., Brouki Milan, P., Kargozar, S., Baino, F., Mobasheri, A., Mozafari, M. (2022). Additive manufacturing of bioactive glass biomaterials. Methods, 208, 75-91.
21. Madamsetty, V.S., Mohammadinejad, R., Uzielienė, I., Nabavi, N., Dehshahri, A., García-Couce, J., Tavakol, S., Moghassemi, S., Dadashzadeh, A., Makvandi, P., Pardakhty, A., Aghaei Afshar, A., Seyfoddin, A. (2022). Dexamethasone: insights into pharmacological aspects, therapeutic mechanisms, and delivery systems. ACS Biomaterials Science & Engineering, 8(5), 1763-1790.
22. Mobasheri, A. (2022). "Self-Healing": A novel and integrated multimodal concept for the management of musculoskeletal pain. Journal of Pain Research, 15, 3479-3482.
23. Žėkas, V., Kurg, R., Kurg, K., Bironaitė, D., Radzevičius, M., Karčiauskaitė, D., Matuzevičienė, R., Kučinskienė, Z.A. (2022). Oxidative properties of blood-derived extracellular vesicles in 15 patients after myocardial infarction.  Medical Sciience Monitor, 28, e935291.

Publikacijos kituose recenzuojamuose mokslo leidiniuose:

1. Rios, J.L., Sapède, D., Djouad, F., Rapp, A.E., Lang, A., Larkin, J., Ladel, C., Mobasheri, A. (2022). Animal models of osteoarthritis part 1-preclinical small animal models: challenges and opportunities for drug development. Current Protocols, 2(11), e596.
2. Karsdal, M.A., Tambiah, J., Hochberg, M.C., Ladel, C., Bay-Jensen, A.C., Arendt-Nielsen, L., Mobasheri, A., Kraus, V.B. (2022). Reflections from the 2021 OARSI clinical trial symposium: Considerations for understanding biomarker assessments in osteoarthritis drug development - should future studies focus on disease activity, rather than status? Osteoarthritis and Cartilage Open, 4(3), 100262.

2021 metai

Publikacijos leidiniuose, referuojamuose ir turinčiuose citavimo indeksą mokslinės informacijos instituto duomenų bazėje "Clarivate Analytivs Web of Science:

1. Arden, N.K., Perry, T.A., Bannuru, R.R., Bruyère, O., Cooper, C., Haugen, I.K., Hochberg, M.C., McAlindon, T.E., Mobasheri, A., Reginster, J.Y. (2021). Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines. Nature Reviews Rheumatology, 17(1), 59-66.
2. Yamada, S., Suzuki, Y., Bernotienė, E., Giles, W.R., Imaizumi, Y., Yamamura, H. (2021). Swelling-activated ClC-3 activity regulates prostaglandin E2 release in human OUMS-27 chondrocytes. Biochemical and Biophysical Research Communications, 537, 29-35.
3. Zheng, L., Zhang, Z., Sheng, P., Mobasheri, A. (2021). The role of metabolism in chondrocyte dysfunction and the progression of osteoarthritis. Ageing Research Reviews, 66, 101249.
4. Uzielienė, I., Kalvaitytė, U., Bernotienė, E., Mobasheri, A. (2021). Non-viral gene therapy for osteoarthritis. Frontiers in Bioengineering and Biotechnology, 8, 1519.
5. Mobasheri, A. (2021). Biosensors for the multiplex detection of inflammatory disease biomarkers. Biosensors-Basel, 11(1), E11.
6. De Francesco, F., Matta, C., Riccio, M., Sbarbati, A., Mobasheri, A. (2021). Reevolution of tissue regeneration: from recent advances in adipose stem cells to novel therapeutic approaches. Stem Cells International, 2021, 2179429.
7. Lane, N.E., Ivanova, J., Emir, B., Mobasheri, A., Jensen, M.G. (2021). Characterization of individuals with osteoarthritis in the United States and their use of prescription and over-the-counter supplements. Maturitas, 145, 24-30.
8. Matta, C., Fellows, C.R., Quasnichka, H., Williams, A., Jeremiasse, B., Allaway, D., Mobasheri, A. (2021). Clusterin secretion is attenuated by the proinflammatory cytokines interleukin-1 beta and tumor necrosis factor-alpha in models of cartilage degradation. Journal Of Orthopaedic Research, 39(5), 1017-1029.
9. Kemppi, H., Finnila, M.A., Lorite, G.S., Nelo, M., Juuti, J., Kokki, M., Kokki, H., Rasanen, J., Mobasheri, A. Saarakkala, S. (2021). Design and development of poly-L/D-lactide copolymer and barium titanate nanoparticle 3D composite scaffolds using breath figure method for tissue engineering applications. Colloids And Surfaces B-Biointerfaces, 199, 111530.
10. Cordero-Barreal, A., Gonzalez-Rodriguez, M., Ruiz-Fernandez, C., Eldjoudi, D.A., AbdElHafez, Y.R.F., Lago, F., Conde, J., Gomez, R., Gonzalez-Gay, M.A., Mobasheri, A., Pino, J., Gualillo, O. (2021). An update on the role of leptin in the immuno-metabolism of cartilage. International Journal Of Molecular Sciences, 22(5), 2411.
11. Uzielienė, I., Bagdonas, E., Hoshi, K., Sakamoto, T., Hikita, A., Tachtamiševaitė, Ž., Rakauskienė, G., Kvederas, G., Mobasheri, A., Bernotienė, E. (2021). Different phenotypes and chondrogenic responses of human menstrual blood and bone marrow mesenchymal stem cells to activin A and TGF-β3. Stem Cell Research & Therapy, 12(1), 251.
12. Rinkūnaitė, I., Šimoliūnas, E., Bironaitė, D., Rutkienė, R., Bukelskienė, V., Meškys, R., Bogomolovas, J. (2021). The effect of a unique region of parvovirus B19 capsid protein VP1 on endothelial cells. Biomolecules, 11(4), 606.
13. Stulpinas, A., Užusienis, T., Imbrasaitė, A., Krestnikova, N., Ungurytė, A., Kalvelytė, A.V. (2021). Cell-cell and cell-substratum contacts in the regulation of MAPK and Akt signalling: Importance in therapy, biopharmacy and bioproduction. Cellular Signalling, 84, 110034.
14. Dallo, I., Szwedowski, D., Mobasheri, A., Irlandini, E., Gobbi, A. (2021). A prospective study comparing leukocyte-poor platelet-rich plasma combined with hyaluronic acid and autologous microfragmented adipose tissue in patients with early knee osteoarthritis. Stem Cells and Development, 30(13), 651-659.
15. Saberi, M., Zhang, X.L., Mobasheri, A. (2021). Targeting mitochondrial dysfunction with small molecules in intervertebral disc aging and degeneration. GeroScience, 43(2), 517-537.
16. Ahmadi, A., Niknahad, H., Li, H.F., Mobasheri, A., Manthari, R.K., Azarpira, N., Mousavi, K., Khalvati, B., Zhao, Y.F., Sun, J.Y., Zong, Y.Q., Ommati, M.M., Heidari, R. (2021). The inhibition of NF kappa B signaling and inflammatory response as a strategy for blunting bile acid-induced hepatic and renal toxicity. Toxicology Letters, 349, 12-29.
17. Mobasheri, A., Fonseca, J.E., Gualillo, O., Henrotin, Y., Largo, R., Herrero-Beaumont, G., Rocha, F.A.C. (2021). Editorial: inflammation and biomarkers in osteoarthritis. Frontiers in Medicine, 8, 727700.
18. Mobasheri, A., Trumble, T.N., Byron, C.R. (2021). Editorial: one step at a time: advances in osteoarthritis. Frontiers in Veterinary Science, 8, 727477.
19. Briggs, A.M., Schneider, C.H., Slater, H., Jordan, J.E., Parambath, S., Young, J.J., Sharma, S., Kopansky-Giles, D., Mishrra, S., Akesson, K.E., Ali, N., Belton, J., Betteridge, N., Blyth, F.M., Brown, R., Debere, D., Dreinhofer, K.E., Finucane, L., Foster, H.E., Gimigliano, F., Haldeman, S., Haq, S.A., Horgan, B., Jain, A., Joshipura, M., Kalla, A.A., Lothe, J., Matsuda, S., Mobasheri, A., Mwaniki, L., Nordin, M.C., Pattison, M., Reis, F.J.J., Soriano, E.R., Tick, H., Waddell, J., Wiek, D., Woolf, A.D., March, L. (2021).  . BMJ Global Health, 6(6), 006045.
20. Wang, S.Y., Mobasheri, A., Zhang, Y., Wang, Y.L., Dai, T.Q., Zhang, Z.Y. (2021). Exogenous stromal cell-derived factor-1 (SDF-1) suppresses the NLRP3 inflammasome and inhibits pyroptosis in synoviocytes from osteoarthritic joints via activation of the AMPK signaling pathway. Inflammopharmacology, 29(3), 695-704.
21. Szwedowski, D., Szczepanek, J., Paczesny, L., Zabrzynski, J., Gagat, M., Mobasheri, A., Jeka, S. (2021). The effect of platelet-rich plasma on the intra-articular microenvironment in knee osteoarthritis. International Journal of Molecular Sciences, 22(11), 5492.
22. Sunkara, V., Heinz, G.A., Heinrich, F.F., Durek, P., Mobasheri, A., Mashreghi, M.F., Lang, A. (2021). Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee jodint. Osteoarthritis and Cartilage, 29(6), 905-914.
23. Ommati, M.M., Mobasheri, A., Heidari, R. (2021). Drug-induced organ injury in coronavirus disease 2019 pharmacotherapy: Mechanisms and challenges in differential diagnosis and potential protective strategines. Journal of Biochemical and Molecular Toxicology, 35(7), e22795.
24. Bradūnaitė, R., Leonavičienė, L., Akramas, A., Vasiliauskas, A., Dumalakienė, I., Vilienė, R., Jonauskienė, I., Mackiewicz, Z., Leonavičiūtė-Klimantavičienė, M. (2021). The effect of complex herbal extract and methotrexate on suppressing adjuvant arthritis in rats. Veterinarski Arhiv, 91 (4), 411-425.
25. Matta, C., Lewis, R., Fellows, C., Diszhazi, G., Almassy, J., Miosge, N., Dixon, J., Uribe, M.C., May, S., Poliska, S., Barrett-Jolley, R., Fodor, J., Szentesi, P., Hajdú, T., Keller-Pinter, A., Henslee, E., Labeed, F.H., Hughes, M.P., Mobasheri, A. (2021). Transcriptome-based screening of ion channels and transporters in a migratory chondroprogenitor cell line isolated from late-stage osteoarthritic cartilage. Journal of Cellular Physiology, 236(11), 7421-7439.
26. Ruiz-Fernandez, C., Gonzalez-Rodriguez, M., Francisco, V., Rajab, I.M., Gomez, R., Conde, J., Lago, F., Pino, J., Mobasheri, A., Gonzalez-Gay, M.A., Mera, A., Potempa, L.A., Gualillo, O. (2021).  Monomeric C reactive protein (mCRP) regulates inflammatory responses in human and mouse chondrocytes. Laboratory Investigation, 101(12), 1550-1560.
27. Mobasheri, A., Mahmoudian, A., Kalvaitytė, U., Uzielienė, I., Larder, C.E., Iskandar, M.M., Kubow, S., Hamdan, P.C., de Almeida, C.S., Favazzo, L.J., van Loon, L.J.C., Emans, P.J., Plapler, P.G., Zuscik, M.J. (2021). A white paper on collagen hydrolyzates and ultrahydrolyzates: potential supplements to support joint health in osteoarthritis? Current Rheumatology Reports, 23(11), 78.
28. Uzielienė, I., Bironaitė, D., Bernotas, P., Sobolev, A., Bernotienė, E. (2021). Mechanotransducive biomimetic systems for chondrogenic differentiation in vitro. International Journal of Molecular Sciences, 22(18), 9690.
29. Mikšiūnas, R., Aldonytė, R., Vailionytė, A., Jelinskas, T., Romuald Eimont, R., Stankevičienė, G., Cėpla, V., Valiokas, R., Ručinskas, K., Janušauskas, V., Labeit, S., Bironaitė, D. (2021). Cardiomyogenic differentiation potential of human dilated myocardium-derived mesenchymal stem/stromal cells: the impact of HDAC inhibitor SAHA and biomimetic matricos. International Journal of Molecular Sciences, 22(23), 12702.
30. Vaičiulevičiūtė, R., Bironaitė, D., Uzielienė, I., Mobasheri, A., Bernotienė, E. (2021). Cardiovascular drugs and osteoarthritis: effects of targeting ion channels. Cells, 10(10), 2572.
31. Van Helvoort, E.M., Welsing, P.M.J, Jansen, M.P., Gielis, W.P., Loef, M., Kloppenburg, M., Blanco, F., Haugen, I.K., Berenbaum, F., Bay-Jensen, A.C., Ladel, C., Lalande, A., Larkin, J., Loughlin, J., Mobasheri, A., Weinans, H., Lafeber, F., Eijkelkamp, N., Mastbergen, S. (2021). Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping. RMD Open, 7(3), e002025.
32. Poletti, F., González-Fernández, R., García, M.D., Rotoli, D., Ávila, J., Mobasheri, A., Martín-Vasallo, P. (2021). Molecular-morphological relationships of the scaffold protein FKBP51 and inflammatory processes in knee osteoarthritis. Cells, 10(9), 2196.
33. Conde, J., Ruiz-Fernandez, C., Francisco, V., Scotece, M., Gómez, R., Lago, F., Gonzalez-Gay, M.A., Pino, J., Mobasheri, A., Gualillo, O. (2021). Dickkopf-3 (DKK3) signaling in IL-1α-challenged chondrocytes: involvement of the NF-κB pathway. Cartilage, 13(2 suppl), 925S-934S.
34. Szwedowski, D., Ambrozy, J., Grabowski, R., Dallo, I., Mobasheri, A. (2021). Diagnosis and treatment of the most common neuropathies following knee injuries and reconstructive surgery-A narrative review. Heliyon, 7(9), e08032.
35. Dehshahri, A., Kumar, A., Madamsetty, V.S., Uzielienė, I., Tavakol, S., Azedi, F., Fekri, H.S., Zarrabi, A., Mohammadinejad, R., Thakur, V.K. (2021). New horizons in hydrogels for methotrexate delivery. Gels, 7(1), 2.

Publikacijos kituose recenzuojamuose mokslo leidiniuose:

1. Uzielienė, I., Denkovskij, J., Bernotienė, E., Kalvaitytė, U., Vaičiulevičiūtė, R., Ramos, Y.F.M., Mobasheri, A. (2021). Protocol for the isolation of intact chondrons from healthy and osteoarthritic human articular cartilage. In Methods in Molecular Biology, 2245, 13-22.
2. Ramos, Y.F.M., Mobasheri, A. (2021). MicroRNAs and Regulation of Autophagy in Chondrocytes. In Methods in Molecular Biology, 2245, 179-194.
3. Žiniauskaitė, A., Cėpla, V., Jelinskas, T., Eimont, R., Ulčinas, A., Aldonytė, R., Valiokas, R., Kalesnykas, G., Hakkarainen, J.J. (2021). Introducing an efficient in vitro Cornea mimetic model for testing drug permeability. Sci, 3(3), 30.
4. Vaičiulevičiūtė, R., Kalvaitytė, U., Bernotienė, E., Mobasheri, A. (2021). Ion channel modulators for treatment-resistant rheumatoid arthritis: focus on inflammation.  Bioelectricity, 3(4), 243-248.
5. Guerrina, R., Borisch, B., Callahan, L.F., Howick, J., Reginster, J.Y., Mobasheri, A. Health and gender inequalities of the COVID-19 pandemic: adverse impacts on women's health, wealth and social welfare. (2021). Frontiers in Global Women's Health, 2, 670310.
6. Mobasheri A. (2021). Women's health: A revised global agenda in the COVID-19 era? Case Reports in Women's Health, 30, e00292.
7. Mobasheri, A., Im, G.-I., Katz, J.N., Loughlin, J., Kraus, V.B., Sandell, L.J., Berenbaum, F., Abramson, S., Lotz, M., Hochberg, M., Pelletier, J.-P., Madry, H., Block, J.A., Lohmander, L.S., Altman, R.D. (2021). Osteoarthritis Research Society International (OARSI): Past, present and future. Osteoarthritis and Cartilage Open, 3(2), 100146.

2020 metai

Publikacijos leidiniuose, referuojamuose ir turinčiuose citavimo indeksą mokslinės informacijos instituto duomenų bazėje "Clarivate Analytivs Web of Science:

1. Mobasheri, A., Richardson, S.M. (2020). Cell and gene therapy for spine regeneration: mammalian protein production platforms for overproduction of therapeutic proteins and growth factors. Neurosurgery Clinics of North America, 31(1), 131-139.
2. Mikšiūnas, R., Mobasheri, A., Bironaitė, D. (2020). Homeobox genes and homeodomain proteins: new insights into cardiac development, degeneration and regeneration. Advances in Experimental Medicine and Biology, 6(1212), 155-178.
3. Baltrūnienė, V., Rinkūnaitė, I., Bogomolovas, J., Bironaitė, D., Kažukauskienė, I., Šimoliūnas, E., Ručinskas, K., Puronaitė, R., Bukelskienė, V., Grabauskienė, V. (2020). The role of cardiac T-cadherin in the indicating heart failure severity of patients with non-ischemic dilated cardiomyopathy. Medicina, 56(1), 27.
4. Zachut, M., Šperanda, M., de Almeida, A.M., Gabai, G., Mobasheri, A., Hernández-Castellano, L.E. (2020). Biomarkers of fitness and welfare in dairy cattle: healthy productivity. Journal of Dairy Research, 87(1), 4-13.
5. Haidar, O., O'Neill, N., Staunton, C.A., Bavan, S., O'Brien, F., Zouggari, S., Sharif, U., Mobasheri, A., Kumagai, K., Barrett-Jolley, R. (2020). Pro-inflammatory cytokines drive deregulation of potassium channel expression in primary synovial fibroblasts. Frontiers in Physiology, 11, 226.
6. Mohammadinejad, R., Ashrafizadeh, M., Pardakhty, A., Uzielienė, I., Denkovskij, J., Bernotienė E., Janssen, L., Lorite, G.S., Saarakkala, S., Mobasheri, A. (2020). Nanotechnological strategies for osteoarthritis diagnosis, monitoring, clinical management, and regenerative medicine: recent advances and future opportunities. Current Rheumatology Reports, 22(4), 12.
7. Janssen, L., Saranya, M., Leinonen, M., Pitkanen, O., Mobasheri, A., Lorite, G.S. (2020). Vertically aligned carbon nanotube micropillars induce unidirectional chondrocyte orientation. Carbon, 158, 681-689.
8. Conde, J., Ruiz-Fernandez, C., Francisco, V., Scotece, M., Gomez, R., Lago, F., Gonzalez-Gay, M.A., Pino, J., Mobasheri, A., Gualillo, O. (2020). Dickkopf-3 (DKK3) signaling in IL-1 alpha-challenged chondrocytes: involvement of the NF-kappa B pathway. Cartilage, Article number: UNSP 1947603520933328.
9. Mobasheri, A. (2020). Future Cell and Gene Therapy for Osteoarthritis (OA): Potential for Using Mammalian Protein Production Platforms, Irradiated and Transfected Protein Packaging Cell Lines for Over-Production of Therapeutic Proteins and Growth Factors. In Advances in Experimental Medicine and Biology (1247), Cell Biology and Translational Medicine, 8, 17-31.
10. Mikšiūnas, R., Ručinskas, K., Janušauskas, V., Labeit, S., Bironaitė, D. (2020). Histone deacetylase inhibitor suberoylanilide hydroxamic acid improves energetic status and cardiomyogenic differentiation of human dilated myocardium-derived primary mesenchymal cells. International Journal of Molecular Sciences, 21(14), 4845.
11. Widera, P., Welsing, P.M.J., Ladel, C., Loughlin, J., Lafeber, F.P.F.J., Petit Dop, F., Larkin, J., Weinans, H., Mobasheri, A., Bacardit, J. (2020). Multi-classifier prediction of knee osteoarthritis progression from incomplete imbalanced longitudinal data. Scientific Reports, 10(1), 8427.
12. van Helvoort, E.M., van Spil, W.E., Jansen, M.P., Welsing, P.M.J., Kloppenburg, M., Loef, M., Blanco, F.J., Haugen, I.K., Berenbaum, F., Bacardit, J., Ladel, C.H., Loughlin, J., Bay-Jensen, A.C., Mobasheri, A., Larkin, J., Boere, J., Weinans, H.H., Lalande, A., Marijnissen, A.C.A., Lafeber, F.P.J.G. (2020). Cohort profile: The applied public-private research enabling osteoarthritis clinical headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predict phenotypes of osteoarthritis using clinical, imaging and biochemical markers. BMJ Open, 10(7), e035101.
13. Petronienė, J., Morkvėnaitė-Vilkončienė, I., Mikšiūnas, R., Bironaitė, D., Ramanavičienė, A., Mikoliūnaitė, L., Kisieliūtė, A., Ručinskas, K., Janušauskas, V., Plikusienė, I., Labeit, S., Ramanavičius, A. (2020). Evaluation of redox activity of human myocardium-derived mesenchymal stem cells by scanning electrochemical microscopy. Electroanalysis, ‏32(6) , 1337-1345.
14. Mobasheri, A. (2020). COVID-19, companion animals, comparative medicine, and one health. Frontiers in Veterinary Science, 7, 522.
15. Lee, H., Kim, H., Seo, J., Choi, K., Lee, Y., Park, K., Kim, S., Mobasheri, A., Choi, H. (2020). TissueGene‑C promotes an anti‑infammatory micro‑environment in a rat monoiodoacetate model of osteoarthritis via polarization of M2 macrophages leading to pain relief and structural improvement. Inflammopharmacology, 28(5), 1237-1252.
16. Bernotienė, E., Bagdonas, E., Kirdaitė, G., Bernotas, P., Kalvaitytė, U., Uzielienė, I., Thudium, C.S., Hannula, H., Lorite, G.S., Dvir-Ginzberg, M., Guermazi, A., Mobasheri, A. (2020). Emerging technologies and platforms for the immunodetection of multiple biochemical markers in osteoarthritis research and therapy. Frontiers in Medicine, 7, 572977.
17. Petronienė, J., Morkvėnaitė-Vilkončienė, I., Mikšiūnas, R., Bironaitė, D., Ramanavičienė, A., Ručinskas, K., Janušauskas, V., Ramanavičius, A. Scanning electrochemical microscopy for the investigation of redox potential of human myocardium-derived mesenchymal stem cells grown at 2D and 3D conditions. Electrochimica Acta, 360, 136956.
18. Mobasheri, A., Choi, H., Martin-Vasallo, P. (2020). Over-production of therapeutic growth factors for articular cartilage regeneration by protein production platforms and protein packaging cell lines. Biology-Basel, 9(10): 330.
19. Kulvinskienė, I., Aldonytė, R., Mikšiūnas, R., Mobasheri, A., Bironaitė, D. (2020). Biomatrices for heart regeneration and cardiac tissue modelling in vitro. Advances in Experimental Medicine and Biology, 1298, 43-77.
20. Bradūnaitė, R., Leonavičienė, L., Akramas, L., Leonavičiūtė-Klimantavičienė, M., Vasiliauskas, A., Dumalakienė, I., Jonauskienė, I., Baleišis, J., Mackiewicz, Z. (2020). Anti-inflammatory and antioxidant effects of turmeric extracts in rat adjuvant arthritis. Veterinarski Arhiv, 90 (4), 393-402.
21. Thudium, C.S., Nielsen, S.H., Sardar, S., Mobasheri, A., van Spil, W.E., Lories, R., Henriksen, K., Bay-Jensen, A-C., Karsdal, M.A. (2020). Bone phenotypes in rheumatology - there is more to bone than just bone. BMC Musculoskeletal Disorders, 21(1), 789.
22. Rucins, M., Plotniece, A., Bernotienė, E., Tsai, W-B., Sobolev, A. (2020). Recent approaches to chiral 1,4-dihydropyridines and their fused analogues. Catalysts, 10(9), 1019.
23. Jeremiasse, B., Matta, C., Fellows, C.R., Boocock, D.J., Smith, J.R., Liddell, S., Lafeber, F., van Spil, W.E., Mobasheri, A. (2020). Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines. BMC Molecular and Cell Biology, 21(1), 47.
24. Jarockytė, G., Karabanovas, V., Rotomskis, R., Mobasheri, A. (2020). Multiplexed nanobiosensors: current trends in early diagnostics. Sensors, 20(23), 6890.

Publikacijos kituose recenzuojamuose mokslo leidiniuose:

1. Mobasheri, A., Hinton, M., Shaikh, F., Kubassova, O. (2020). The role of advanced MRI in the development of treat-to-target therapeutic strategies, patient stratification and phenotyping in rheumatoid arthritis. BMC Rheumatology, 4, 33.
2. Mobasheri A. (2020). COVID-19, osteoarthritis and women's health. Case Reports in Women's Health, 27, e00207.
3. Bisenieks, E., Poikans, J., Plotniece, A., Bernotienė, E., Tsai, W.B., Sobolev, A. (2020). Sodium N-(3,5-bis(ethoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine-4-carbonyl)-l-methioninate. Molbank, 3, M1148.
4. Maleckarm M.M., Martín-Vasallo, P., Giles, W.R., Mobasheri, A. (2020).  Physiological effects of the electrogenic eurrent generated by the Na+/K+ Pump in mammalian articular chondrocytes.  Bioelectricity, 2(3), 258-268.

2019 metai

Publikacijos leidiniuose, referuojamuose ir turinčiuose citavimo indeksą mokslinės informacijos instituto duomenų bazėje "Clarivate Analytivs Web of Science:

1. Mobasheri, A., van Spil, W.E., Budd, E., Uzielienė, I., Bernotienė, E., Bay-Jensen, A.C., Larkin, J., Levesque, M.C., Gualillo, O., Henrotin, Y. (2019). Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development: biochemical markers associated with emerging clinical phenotypes and molecular endotypes. Current Opinion in Rheumatology, 31(1), 80–89.
2. Mackiewicz, Z., Mažul, J., Narkevičiūtė, I., Dumalakienė, I., Butrimienė, I., Vilienė, R., Stankevičienė, I., Mieliauskaitė, D. (2019) Sjögren’s syndrome: concerted triggering of sicca conditions. Journal of Immunology Research, Article ID 2075803.
3. Mobasheri, A., Matta, C., Uzielienė, I., Budd, E., Martín-Vasallo, P., Bernotienė, E. (2019). The chondrocyte channelome: A narrative review. Joint Bone Spine, 86(1), 29-35.
4. Kirdaitė, G., Leonavičienė, L., Bradūnaitė, R., Vasiliauskas, A., Rudys, R., Ramanavičienė, A., Mackiewicz, Z. (2019). Antioxidant effects of gold nanoparticles on early stage of collagen-induced arthritis in rats. Research in Veterinary Science, 124, 32–37.
5. Narkevičiūtė, I., Mieliauskaitė, D., Mackiewicz, Z., Butrimienė, I.,  Vilienė, R., Dumalakienė I. (2019). Distribution of myeloid-derived suppressor cells in rheumatoid arthritis and Sjögren’s sindrome. Archives of Rheumatology, 34(1), 53-61.
6. Lewis, R., Álvarez, C.B.G.,  Rayman, M., Lanham-New, S., Woolf, A., Mobasheri, A. (2019). Strategies for optimising musculoskeletal health in the 21st century. BMC Musculoskeletal Disorders, 20, 164.
7. Francisco, V., Ruiz-Fernández, C., Lahera, V., Lago, F., Pino, J., Skaltsounis, L., González-Gay, M.A.,  Mobasheri, A., Gómez, R., Scotece, M., Gualillo, O. (2019). Natural molecules for healthy lifestyles: oleocanthal from extra virgin olive oil. Journal of Agricultural and Food Chemistry, 67(14), 3845−3853.
8. Grauzdytė, D., Raudoniūtė, J., Kulvinskienė, I., Bagdonas, E., Stasiulaitienė, I., Martuzevičius, D., Bironaitė, D., Aldonytė, R., Venskutonis, P.R. (2019). Cytoprotective effects of mangiferin and Z-ligustilide in PAH-Exposed human airway epithelium in vitro. Nutrients, 11(2), 218.
9. Grauzdytė, D., Raudoniūtė, J., Kulvinskienė, I., Bagdonas, E., Stasiulaitienė, I., Martuzevičius, D., Bironaitė, D., Aldonytė, R., Venskutonis, P.R. (2019). Cytoprotective effects of mangiferin and Z-ligustilide in PAH-Exposed human airway epithelium in vitro. Nutrients, 11(2), 218.
10. Matta, C., Boocock, D.J., Fellows, C.R., Miosge, N., Dixon, J.E., Liddell, S., Smith, J., Mobasheri, A. (2019). Molecular phenotyping of the surfaceome of migratory chondroprogenitors and mesenchymal stem cells using biotinylation, glycocapture and quantitative LC-MS/MS proteomic anglysis. Scientific Reports, 9, article number 9018.
11. Emery, C.A., Whittaker, J.L., Mahmoudian, A., Lohmander, L.S., Roos, E.M., Bennell, K.L., Toomey, C.M., Reimer, R.A., Thompson, D., Ronsky, J.L., Kuntze, G., Lloyd, D.G., Andriacchi, T., Englund, M., Kraus, V.B., Losina, E., Bierma-Zeinstra, S., Runhaar, J., Peat, G., Luyten, F.P., Snyder-Mackler, L., Risberg, M.A., Mobasheri, A., Guermazi, A., Hunter, D.J., Arden, N.K. (2019). Establishing outcome measures in early knee osteoarthritis. Nature Reviews Rheumatology, 15(7), 438-448.
12. Rotoli, D., Morales, M., Maeso, M.D., Ávila, J., Pérez-Rodríguez, N.D., Mobasheri, A., van Noorden, C.J.F., Martín-Vasallo, P. (2019). IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment. Journal of Histochemistry & Cytochemistry, 67(7), 481-494.
13. Mobasheri, A., Lambert, C., Henrotin, Y. (2019). Coll2-1 and Coll2-1NO2 as exemplars of collagen extracellular matrix turnover - biomarkers to facilitate the treatment of osteoarthritis? Expert Review of Molecular Diagnostics, 19(9), 803-812.
14. Smith, T.O., Mansfield, M., Hawker, G.A., Hunter, D.J., March, L.M., Boers, M., Shea, B.J., Christensen, R., Guillemin, F., Terwee, C.B., Williamson, P.R., Roos, E.M., Loeser, R.F., Schnitzer, T.J., Kloppenburg, M., Neogi, T., Ladel, C.H., Kalsi, G., Kaiser, U., Buttel, T.W., Ashford, A.E., Mobasheri, A., Ardene, N.K., Tennant, A., Hochberg, M.C., de Witel, M., Tugwell, P., Conaghan, P.G. (2019). Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017. Journal of Rheumatology, 46(8), 976-980.
15. Smith, T.O., Hawker, G.A., Hunter, D.J., March, L.M., Boers, M., Shea, B.J., Christensen, R., Guillemin, F., Terwee, C.B., Williamson, P.R., Dodd, S., Roos, E.M., Loeser, R.F., Schnitzer, T.J., Kloppenburg, M., Neogi, T., Ladel, C.H., Kalsi, G., Kaiser, U., Buttel, T.W., Ashford, A.E., Mobasheri, A., Arden, N.K., Tennant, A., Hochberg, M.C., de Witel, M., Tugwell, P., Conaghan, P.G. (2019). The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis. Journal of Rheumatology, 46(8), 981-989.
16. Kulvinskienė, I., Raudoniūtė, J., Bagdonas, E., Čiužas, D., Poliakovaitė, K., Stasiulaitienė, I., Zabulytė, D., Bironaitė, D., Venskutonis, P.R., Martuzevičius, D., Aldonytė, R. (2019). Lung alveolar tissue destruction and protein citrullination in diesel exhaust-exposed mouse lungs. Basic and Clinical Pharmacology and Toxicology, 125(2), 166-177.
17. Van Spil, W.E., Kubassova, O., Boesen, M., Bay-Jensen, A.C., Mobasheri, A. (2019). Osteoarthritis phenotypes and novel therapeutic targets. Biochemical Pharmacology, 165(SI), 41-48.
18. Francisco, V., Ruiz-Fernandez, C., Pino, J., Mera, A., Gonzalez-Gay, M.A., Gomez, R., Lago, F., Mobasheri, A., Gualillo, O. (2019). Adipokines: Linking metabolic syndrome, the immune system, and arthritic diseases. Biochemical Pharmacology, 165(SI), 196-206.
19. de Almeida, A.M., Zachut, M., Hernández-Castellano, L.E., Šperanda, M., Gabai, G.,  Mobasheri, A. (2019). Biomarkers of fitness and welfare in dairy animals: healthy living. Journal of Dairy Research, 86(4), 379-387.
20. Uzielienė, I., Bernotienė, E., Rakauskienė, G., Denkovskij, J., Bagdonas, E., Mackiewicz, Z., Porvaneckas, N., Kvederas, G., Mobasheri, A. (2019). The antihypertensive drug nifedipine modulates the metabolism of chondrocytes and human bone marrow-derived mesenchymal stem cells. Frontiers in Endocrinology, 10, 756.

Publikacijos kituose recenzuojamuose mokslo leidiniuose:

1. Szychlinska, M.A., Di Rosa, M., Alessandro Castorina, A., Mobasheri, A., Musumeci, G. (2019). A correlation between intestinal microbiota dysbiosis and osteoarthritis. Heliyon, 5(1), Article ID e01134.
2. Mobasheri, A., Saarakkala, S., Finnilä, M., Karsdal, M.A., Bay-Jensen, A.C., van Spil, W.E. (2019). Recent advances in understanding the phenotypes of osteoarthritis. F1000Research, 8, 2091.