DEPARTMENT OF REGENERATIVE MEDICINE
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- DEPARTMENT OF REGENERATIVE MEDICINE
- Vailionyte Agne
2021-10-01 – 2025-09-30
PhD supervisor – dr. Ruta Aldonyte
Topic - Human respiratory system tissue and disease biomodeling in vitro.
- Pachaleva Jolita
2021-10-01 – 2025-09-30
PhD supervisor – dr. Eiva Bernotiene
Topic - Development of stem cell-based technologies for the prevention of degeneration in skeletal tissues and search of regeneration biomarkers.
- Kugaudaite Gabija
2024-10-01 – 2028-09-30
PhD supervisor – dr. Ilona Uzieliene
Topic - Effect of extracellular vesicles of mesenchymal stem cells on cartilage tissue regeneration in vitro.
Fields of the investigation
Principal research topics at the Department of Regenerative Medicine include: studies on the capabilities of cellular therapies for osteoarthritis and cartilage defects, heart and skeletal muscle, chronic obstructive pulmonary disease (COPD) and other degenerative lung diseases, arrhythmias, autoimmune, inflammatory and other diseases; mesenchymal stem cell -based therapies and their cultures in 3D scaffolds for engineering of cartilage, lung, muscle and cardiac tissues, pacemaking technologies; investigation and characterization of aggressive cells in rheumatoid synovium and progenitor cells in cartilage; mechanotransduction and calcium signaling in cartilage and cardiac cells, effects of calcium channel inhibitors, epigenetic changes, including methyl, acetyl and other groups, modifying agents and their effect to the cells; application of photodynamic therapy, nanomedicine and others.
The search of disease biomarkers for osteoarthritis and development of multiplexed immunodetection nanobiosensor are the important fields of our interests at the department. We also work in the area of respiratory health assessing mechanisms of injury, i.e. cigarette smoking, air pollution etc., designing novel models and markers for in vitro studies and investigating novel candidate therapies.
